Dermatitis Herpetiformis Pictures

Jun 22 2011 Published by admin under Uncategorized

What is Dermatitis Herpetiformis?

Dermatitis Herpetiformis, otherwise known as Duhring’s disease, is a chronic autoimmune blistering dermatological condition characterized by clustered excoriations, urticaria and vesicles located on the elbows, knees, back and buttocks. As the name suggests, the inflammation is similar to herpes, but it is not related to herpes virus. It was Dr. Louis Duhring who originally described the disease in the year 1884 at the University of Pennsylvania.

The papulovesicular eruptions are intensely itchy and chronic distributed symmetrically on extensor surfaces. This condition also involves the appearance of a rash. The rash results when gluten joins with IgA, both enter the bloodstream and circulates in the system and finally, gluten and IgA clog up the small blood vessels in the skin. This will draw neutrophils and release chemicals which really produce the rash. At first, the person will notice a slight pigmentation at the site where the lesions come out. Then later it will become vesicles that occur in groups.

Dermatitis herpetiformis responds well to Dapsone. For most patients, this drug is an effective treatment that will improve the disease in just a few days. It responds so quickly that itching is significantly reduced in two to three days. However, when the damage has reached the gastrointestinal tract, this pharmacological treatment has no effect.

To help control the disease, a strict gluten-free diet should be observed as lifetime management. This modification can radically decrease related intestinal damage and other complications.

No responses yet

Erythema Multiforme Pictures

Jun 22 2011 Published by admin under Uncategorized

What is Erythema multiforme?

Erythema multiforme is a common dermatological condition of idiopathic origin, potentially mediated by the accumulation of immune complex in the microvasculature surface of the skin and mucosa. It is a severe, self-limiting inflammatory skin condition under type IV hypersensitivity reaction triggered by the exposure to certain medications, contagion and other factors. In general, it affects the young population.

Symptoms

Erythema multiforme minor

Of the two types, EM minor is the less serious and accounts for 80% of Erythema multiforme cases. The rash comes out over a few days somewhat expanding to around 2 cm. but in some patients more than a few crops go after each other in single attack. Slight burning or mild itch may be existing but becomes most intense over the back of the hands and feet. Classically, the rash appears as bull’s eye shaped circles on the palms arranged symmetrically and lasts for 7 to 14 days and then resolves leaving a remaining brown colored discoloration. There is an involvement of the oral mucosa for 70% of the cases. Oral lesions in the lips, palate, and gums are common. The eyes are affected. There are red conjunctivae and eye swelling and excessive tearing. There are also excruciating erosions on the genitals.

Stevens Johnson syndrome

In this situation, there is larger injury. Together with the erythematous eruption, there are a few significant hemorrhagic blisters present. There are extensive blood blisters predominant on the torso and face.

Causes

The Pathophysiology of Erythema multiforme is not yet fully implicated but it appears that there is a taking part of the cell-mediated hypersensitivity reaction by the immune system that can be elicited by variety of stimuli, specifically bacteria, viruses and chemicals.

As revealed in a current global future analysis, the most important cause of Erythema multiforme is Herpes simplex virus, but bacterial, parasitic and fungal infections are also correlated. In the case of Stevens-Johnson syndrome and toxic epidermal necrolysis, it looks to play a smaller role. Drugs were found to be a more universal trigger for these cases. For Erythema Multiforme minor and major, the principal risk factor is history of herpes infection or recurrent case of herpes.

Treatment

The treatment starts with identifying the activating factor and removing it, however, this is not all the time achievable. If drug is the culprit, it must be discontinued as soon as possible. If the cause is infection, it must then be properly treated following the performance of diagnostic tests.

Erythema multiforme minor is typically without a clinical symptom therefore requires no treatment, as the lesions are self-limiting and will disappear within a month. If EM minor is herpes virus induced, Zovirax is useful.

Mild cases of Erythema multiforme require only symptomatic management. Give analgesics as needed, skin care; topical steroids, and soothing mouthwash and gargles. Aggressive observation and fluids and electrolytes replacement are of dominant significance.

No responses yet

Scabies Pictures

Jun 22 2011 Published by admin under Uncategorized

What is Scabies?

Conversationally established as the seven-year itch, Scabies is a highly communicable skin infection described by the eruptive lesions created from the skin excavations of the female itch mites called Sarcoptes scabiei. These eight-legged parasites are microscopic measuring around 0.33 to 0.45 mm but at times they are detectable as white pinpoints so a magnifying glass is of use. The parasite burrows underneath the epidermis to lay eggs and initiates an intense allergic irritation.

Scabies Causes

Any person can develop infection or re-infection since it is easily spread most often by prolonged, direct physical contact with infected individuals. The disease may also be transmitted from inanimate objects or by sexual contact. The time-span needed for the female itch mite to burrow on infected skin and lay eggs is within a day from the initial contact with the infected individual.

Scabies Symptoms

The clinical manifestations involve intense and unrelenting itchiness which becomes worse at night and after a hot shower. There are also superficial burrows which are often linear or s-shaped and come out as tiny, wavy, flushed, grayish or dark outlines on the skin surface, especially on the folds under the arms, around the wrists and between the fingers, and other moist areas. When larger areas of the body are involved and secondary infection is serious, hyperthermia, headache and body weakness will occur.

Scabies Treatment

This infection is more frequently observed in congested vicinities with insanitary living situations. It is a sign of poor hygiene. Care must be observed regarding effective preventive measures including good personal hygiene, regular changing of clean clothing, beddings and towels, exposing the linens used under the sun, washing used linens in hot water, general house cleaning and improving the sanitation of the environment. Stuffed toys can be wrapped up in a plastic bag for three days because the parasites cannot live on for too long being away from host’s skin. All rooms in the residence have got to be vacuumed and the bag should then be destroyed.

The medical management includes assessing the whole family of the infected individual before assuming any treatment, for as long as one member stays infected, others will potentially get the disease. Dermatologists treat this infection by recommending a medicated lotion to destroy the itch mites. People are instructed to apply permethrin cream from the neck down and let it remain on the skin during the night before it is washed off. This cream application is regularly repeated in a week. Benzyl benzoate emulsion and Kwell ointment are effective but should be limitedly applied entirely to the skin.

No responses yet

Psoriasis Pictures

Jun 20 2011 Published by admin under Uncategorized

What is Psoriasis?

Psoriasis is a common T-cell-mediated autoimmune, persistent skin disorder, characterized by circumscribed patches of raised, thickened, red bumps covered with silvery-white, flaking scales. Naturally in the deepest layer of skin, there are new skin cells continuously being formed. From there, they ascend to the epidermal layer where dead surface cells are shed in a 28-day-process. In areas affected by psoriasis, however, the problem is new cells only need three to four days to reach the epidermal surface, leading to an increased epidermal cell turnover with marked thickening which causes the typical scaly plaques.

In almost all cases, the primary cause is unspecified. It is believed that activated T lymphocytes produce chemical messengers that stimulate abnormal growth of keratinocytes and dermal blood vessels. Other factors may be associated with heredity. Flare-ups may be elicited by infection, skin trauma and injury, stress, certain medications, corticosteroid withdrawal, alcohol and cold temperature and various environmental factors.

There is no known way to prevent psoriasis, and there is no cure either. The primary goal of treatment is to suppress the signs and symptoms of the disease. The treatment regimen depends on the severity of the condition as well as the patient’s age, history, compliance to therapy, and sex.

Exposure to sunlight improves many individuals with the condition. Maintaining the skin soft and well moisturized is effective. Application of heavy moisturizing creams can prevent skin dehydration especially when applied straight away after bathing. Never use irritating cosmetics and soaps. Do no scratching or skin rubbing or any aggressive action which can cause bleeding and irritation. Bath soaks with coal tar can eliminate and trim down the plaques. A physician-directed light therapy may be necessary.

The three fundamental modes of treatments for psoriasis are topical therapy, phototherapy and systemic therapy; all these therapies may well be used unaccompanied or in combination. Under topical therapy, the major remedies are corticosteroids, vitamin D-3 derivatives, coal tar and retinoids. In cases where psoriasis is extensive, as characterized by more itchy patches than can simply be counted, then UV-B light and PUVA are used. The third treatment mode is systemic therapy which includes drugs that are usually established after both topical treatment and light therapy have become unsuccessful.

No responses yet

Eczema Pictures

Jun 20 2011 Published by admin under Uncategorized

What is Eczema?

Eczema is a general term used for common inflammatory dermatological conditions. The most constant features of eczema which are associated to significant amounts of histamine on the skin are pruritus and hyperirritability. Because of the alteration in the lipid content, sebaceous gland activity and sweating, too much dryness with consequential itching develops. This leads to crusting, flaking, cracking and bleeding of the skin. In reaction to skin rubbing, instant redness comes out on the skin. Scratching exposes a healing lesion which may increase the rash. Over time, burning cracks become visible.

The common classifications of eczema are atopic eczema, contact dermatitis, xerotic eczema and seborrheic dermatitis. Atopic eczema is an allergic disease with a hereditary element. Contact dermatitis is a cell-mediated skin sensitivity which results from a direct exosure with a chemical or allergen. A very common skin disorder among the older population is xerotic eczema where the skin becomes so dehydrated it turns into eczema. This type of eczema gets worse in dry winter conditions. Seborrheic dermatitis is a skin condition directly related to dandruff. There is dry and oily flaking in the scalp, face and eyebrows.

Eczema can be genetically inherited but still there is no exact cause but a defect of the skin weakens its role as a barrier. Some people have more than one gene defect leading to abnormalities in proteins which are known to be essential in maintaining skin integrity. Some forms of eczema can be triggered by environmental allergens direct contact with irritants, temperature, humidity, and psychological stress.

The course of action for the treatment of eczema includes decreasing irritation and scratching, lubricating the skin and preventing secondary infections. Individuals should stay away from allergenic substances such as harsh soaps and detergents. Scratching the affected area must be avoided since it will just worsen the condition ang may spread the irritation. Keep the fingernails short and clean. To prevent it from being scratched, it is effective to cover the area with clothing or sterile bandage. If exposed to allergenic substances, immediate washing of the exposed area with soap ang running water can remove the irritating chemical. To soothe the skin, intermittently apply wet compresses for short periods. OTC corticosteroid creams and oral antihistamines can help to relieve the intense itching. If secondary bacterial infection develops, antibiotics may well be needed.

No responses yet

Contact Dermatitis Pictures

Jun 20 2011 Published by admin under Uncategorized

What is Contact Dermatitis?

Contact dermatitis is a medical term for skin inflammation that results from exposure of the skin to an external chemical or physical substance, which can be an irritant or an allergen.

About 80% of the cases of contact dermatitis are caused by irritants. The inflammatory reaction is attributable to the direct effect of irritant substances like soaps, plants, solvent, latex, cosmetics, food, and detergents on the skin.

The remaining 20% of the cases are accounted to allergic contact dermatitis which is also the most prevalent type of immunotoxicity. In this case, the skin inflammation is caused by a hypersensitivity reaction acting via the interaction of the immune system’s immunoregulatory cytokines and T lymphocyte subpopulations to a specific substance. It begins with the chemical breaking through the skin. It binds to Langerhans’ cells and travel to lymph glands close by. Sensitization ends when the allergen has been introduced to T-lymphocytes which will produce memory cells to remember that specific allergen. A previous exposure to the substance is needed to provoke allergy. Succeeding exposure causes the T-lymphocytes to recognize the allergen and activates them, releasing inflammatory mediators to the site.

Formaldehyde, rubber, fragrances, nickel, topical medications, hair salon chemicals and some plants are the commonest allergens. In this case, there is a delay of the immune response between the first exposure and the consequent reaction.

Another difference between the two types of dermatitis is the extent of inflammation as manifested in the skin surface. Usually, allergic dermatitis is confined to an area where the trigger was actually in contact with the skin while in irritant, the skin inflammation is more widespread.

The common reaction is a red rash which appears immediately in irritant contact dermatitis while the rash brought by allergic contact dermatitis every so often emerges until 1 to 3 days following an allergen contact. Urticaria appears in a pattern where the skin was directly exposed to a trigger and worsens when the area is scratched.

To discard and inactivate most of the displeasing substance, clean the exposed skin with soap and cool water straight away after direct contact to an identified trigger. Lemon juice and vinegar which are weak acids can be applied to neutralize the effects of the chemical substances. Cold moist compresses are done for 30 minutes thrice a day if there is development of blisters. Aside from application of calamine lotion and cool colloidal baths, Diphenhydramine can be taken to relieve itching.

No responses yet

Herpes Pictures

Jun 20 2011 Published by admin under Uncategorized

What is Herpes?

Herpes simplex is a sexually transmitted viral disease caused either by Herpes simplex virus type and type 2. The categorization into various distinct disorders is based on the site of viral infection.

The virus rotates between episodes of active disease where blisters holding the infectious virus particles appear persisting for about 2 to 21 days. The first period of this disease is typically worse than recurrences that appear in a while. The principal clinical manifestation of herpes is an attack of painful, irritating lesions on and around the reproductive organs or on or by the lips.

This is followed by a remission phase. Subsequent to the preliminary infection, the herpes viruses move all along the path to the ganglion where they become dormant and exist there for lifetime. Individuals can expect an outbreak if a tingling sensation is felt. During this time, they are acutely contagious even if the skin looks natural. Classically, the sores entirely heal but resurface at some time in the future when least anticipated. The reasons as to why the infection recurs are indefinite while a few possible triggers have been recognized together with the use of immunosuppressant medications, excessive sunlight exposure, hyperthermia, stress, acute illness, and weakened immune system.

The virus is easily transmitted by skin-to-skin contact with an active lesion or even with visibly normal skin but is shedding virus, kissing, or body secretions of an infected person. When the blisters have dried up and crusted over, the danger of infectivity is drastically lessened. To infect an individual, the virus penetrates through small breaks or even microscopic injury in the skin or mucous membrane sufficient enough to allow viral entry.

The most dependable technique to avoid the risk of herpes spread is by means of barrier protection. Limiting the number of sexual partners into one is another move toward prevention knowing that the chances of getting infected rises with the number of sexual partners an individual has.

No responses yet